Establishing trimester-specific reference intervals for coagulation parameters in pregnant women in China
Long Zhang, Yifang Shen, Kaiqi Wu, Wei Wang, Xingjun Meng, Bo Zhu · 2026
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Description
Long Zhang and co-authors set pregnancy-specific reference ranges for blood clotting tests in China, in a 2026 study. Pregnancy steadily shifts the clotting system, so ranges borrowed from non-pregnant adults can mislead doctors. Blood from 879 pregnant women and 253 healthy non-pregnant women was tested across eleven clotting measures.
As pregnancy advanced, several clotting times shortened while fibrinogen, D-dimer, and breakdown products rose. The team built separate reference intervals for non-pregnant women and for each trimester, and most differed clearly from one another. Labs can now judge a pregnant patient's results against women at the same stage, which should sharpen calls on clotting risk. The authors note the ranges come from one population and testing setup, so other regions may need their own.
Catalog record
| CREATOR | Long Zhang, Yifang Shen, Kaiqi Wu, Wei Wang, Xingjun Meng, Bo Zhu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |