Molecular characterization of two conjugative resistance plasmids from a clinical multidrug-resistant ST15 Klebsiella pneumoniae
Ruixue Tao, Meng Li, Nan Zhang, Linke Cao, Jie Zhang, Hanqi Li, Wenbo Yan, Yiming Yang, Tietao Wang, Yani Zhang, Ke Xing · 2026
Read Molecular characterization of two conjugative resistance plasmids from a clinical multidrug-resistant ST15 Klebsiella pneumoniae by Ruixue Tao, Meng Li, Nan Zhang, Linke Cao, Jie Zhang, Hanqi Li, Wenbo Yan, Yiming Yang, Tietao Wang, Yani Zhang, Ke Xing (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13348810.txt.
Description
Ruixue Tao and colleagues study the two resistance plasmids riding in one hospital Klebsiella, in this study from twenty twenty-six. The strain is an ST15 multidrug-resistant Klebsiella pneumoniae from a clinical case. It carried plasmids named pKPA1-1 and pKPA1-2. Both could conjugate, copying themselves into new bacteria.
The two differed in character. The first moved freely, passing into both Klebsiella and Escherichia coli. The second moved only within Klebsiella, but stayed more stable once it arrived. Their drug resistance menus were near-identical. Oddly, gaining either plasmid made the bacterium less virulent, a fitness trade the authors note. The study matters because such plasmids are the courier network of hospital resistance. Knowing their range, stability, and cost helps predict where resistance travels next.
Catalog record
| CREATOR | Ruixue Tao, Meng Li, Nan Zhang, Linke Cao, Jie Zhang, Hanqi Li, Wenbo Yan, Yiming Yang, Tietao Wang, Yani Zhang, Ke Xing |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |