Assessing Surface Binding Events on Golgi Microsomes Isolated from Cancer Cells by Capillary Electrophoresis
Clara Davoine, Gaël Cobraiville, Lionel Pochet, Marianne Fillet · 2026
Read Assessing Surface Binding Events on Golgi Microsomes Isolated from Cancer Cells by Capillary Electrophoresis by Clara Davoine, Gaël Cobraiville, Lionel Pochet, Marianne Fillet (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13347695.txt.
Description
Clara Davoine, Gaël Cobraiville, Lionel Pochet, and Marianne Fillet measure drug binding on tiny membrane sacs taken from cancer cells, in a methods study published in 2026. Golgi sacs keep membrane proteins in near-native settings, yet binding there is hard to read. So capillary flow methods plus new maths were used to get direct affinity values without labels, tags, or large protein excess.
Tests centred on UGCG, a Golgi protein of cancer interest, using fairly even sacs near 150 nm across that kept native inner structure in the reported checks. Tiny sample needs and options for charged or plain compounds widen the method to many membrane targets, offering drug hunters a truer test bed than purified protein alone.
Catalog record
| CREATOR | Clara Davoine, Gaël Cobraiville, Lionel Pochet, Marianne Fillet |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45116 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |