Assessing the suitability of automated registration and segmentation for dosimetry calculations in SIRT treatment planning

Félix Quinton, Romain Popoff, Fabrice Meriaudeau, Jean-Marc Vrigneaud, Olivier Chevallier, Julie Pellegrinelli, Jean-Louis Alberini, Benoit Presles · 2026

Read Assessing the suitability of automated registration and segmentation for dosimetry calculations in SIRT treatment planning by Félix Quinton, Romain Popoff, Fabrice Meriaudeau, Jean-Marc Vrigneaud, Olivier Chevallier, Julie Pellegrinelli, Jean-Louis Alberini, Benoit Presles (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13346394.txt.

Description

Félix Quinton and co-authors test whether full automation can plan liver radiation therapy safely. Their 2026 study uses scans from ninety patients with liver cancer treated by selective internal radiation. Planning needs MRI and CT scans aligned, with liver and tumour outlined, before doses can be computed.

Automatic alignment matched the semi-automatic routine on the liver but wobbled on tumours. Mixed-modality outlining beat single-modality outlining for tumours. Fully automatic doses drifted from the clinic's values by a modest average amount. Single bad outlines, though, swung one dose estimate wildly. An outline overlap of at least 80 percent kept doses safe, the authors find.

Catalog record

CREATORFélix Quinton, Romain Popoff, Fabrice Meriaudeau, Jean-Marc Vrigneaud, Olivier Chevallier, Julie Pellegrinelli, Jean-Louis Alberini, Benoit Presles
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE114 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13346394

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