A human induced pluripotent stem cell model for the holistic study of epithelial-to-mesenchymal transitions
Caroline Hookway, Antoine Borensztejn, Leigh K. Harris, Tiffany Barszczewski, Sara Carlson, Gokhan Dalgin, Suraj Mishra, Ellen M. Adams, Julie C. Dixon, Renske J. Dupar, Jacqueline H. Edmonds, Erik A. Ehlers, Alexandra J. Ferrante, Margaret A. Fuqua, Clare R. Gamlin, Philip Garrison, Janani Gopalan, Benjamin W. Gregor, Maxwell J. Hedayati, Victoria L. Hurless, Kyle N. Klein, Chantelle L. Leveille, Sean L. Meharry, Ricardo Mercado, Haley S. Morris, Gouthamrajan Nadarajan, Nivedita Nivedita, Sandra A. Oluoch, Serge E. Parent, Amber Phan, Brock Roberts, Ashwin Samudre, Emmanuel E. Sanchez, M. Filip Sluzewski, Lev S. Snyder, Derek J. Thirstrup, Hannah F. Thorp, John Paul Thottam, Julia R. Torvi, Gaea Turman · 2026
Read A human induced pluripotent stem cell model for the holistic study of epithelial-to-mesenchymal transitions by Caroline Hookway, Antoine Borensztejn, Leigh K. Harris, Tiffany Barszczewski, Sara Carlson, Gokhan Dalgin, Suraj Mishra, Ellen M. Adams, Julie C. Dixon, Renske J. Dupar, Jacqueline H. Edmonds, Erik A. Ehlers, Alexandra J. Ferrante, Margaret A. Fuqua, Clare R. Gamlin, Philip Garrison, Janani Gopalan, Benjamin W. Gregor, Maxwell J. Hedayati, Victoria L. Hurless, Kyle N. Klein, Chantelle L. Leveille, Sean L. Meharry, Ricardo Mercado, Haley S. Morris, Gouthamrajan Nadarajan, Nivedita Nivedita, Sandra A. Oluoch, Serge E. Parent, Amber Phan, Brock Roberts, Ashwin Samudre, Emmanuel E. Sanchez, M. Filip Sluzewski, Lev S. Snyder, Derek J. Thirstrup, Hannah F. Thorp, John Paul Thottam, Julia R. Torvi, Gaea Turman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13346117.txt.
Description
Caroline Hookway and a large team present a stem cell system, writing in 2026, for watching how epithelial cells change into a more mobile mesenchymal state. Human induced pluripotent stem cells were grown as flat two-dimensional colonies and as hollow three-dimensional forms called lumenoids, giving two views inside one setup.
Fixed and live imaging tracked cell movement, marker proteins, cell junctions, and contact with the basement membrane after the change was triggered. Movement began later in the three-dimensional cultures, and that delay was tied in a measurable way to how intact the membrane stayed. Shared data and tools are offered so other groups can compare results on the same basis.
Catalog record
| CREATOR | Caroline Hookway, Antoine Borensztejn, Leigh K. Harris, Tiffany Barszczewski, Sara Carlson, Gokhan Dalgin, Suraj Mishra, Ellen M. Adams, Julie C. Dixon, Renske J. Dupar, Jacqueline H. Edmonds, Erik A. Ehlers, Alexandra J. Ferrante, Margaret A. Fuqua, Clare R. Gamlin, Philip Garrison, Janani Gopalan, Benjamin W. Gregor, Maxwell J. Hedayati, Victoria L. Hurless, Kyle N. Klein, Chantelle L. Leveille, Sean L. Meharry, Ricardo Mercado, Haley S. Morris, Gouthamrajan Nadarajan, Nivedita Nivedita, Sandra A. Oluoch, Serge E. Parent, Amber Phan, Brock Roberts, Ashwin Samudre, Emmanuel E. Sanchez, M. Filip Sluzewski, Lev S. Snyder, Derek J. Thirstrup, Hannah F. Thorp, John Paul Thottam, Julia R. Torvi, Gaea Turman |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 107013 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |