Evaluation of Chagas TESA VirClia assay for chronic Trypanosoma cruzi infection diagnosis and post-treatment follow-up
Aroa Silgado, Alejandro Mediavilla, Patricia Martínez-Vallejo, Pau Bosch-Nicolau, Carles Rubio-Maturana, Lidia Goterris, Inés Oliveira-Souto, Núria Serre-Delcor, Joan Joseph-Munné, Israel Molina, Elena Sulleiro · 2026
Read Evaluation of Chagas TESA VirClia assay for chronic Trypanosoma cruzi infection diagnosis and post-treatment follow-up by Aroa Silgado, Alejandro Mediavilla, Patricia Martínez-Vallejo, Pau Bosch-Nicolau, Carles Rubio-Maturana, Lidia Goterris, Inés Oliveira-Souto, Núria Serre-Delcor, Joan Joseph-Munné, Israel Molina, Elena Sulleiro (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13343857.txt.
Description
Aroa Silgado and co-authors evaluate a new blood test for chronic Chagas disease in 2026. Diagnosis of Trypanosoma cruzi infection demands two agreeing antibody tests, and cured patients can stay positive for years, so the team checked a chemiluminescence assay built on antigens the parasite itself sheds.
Using 227 stored serum samples judged by two reference tests, the new assay agreed 93.8 percent of the time, with 92 percent sensitivity and full specificity. Cross-reaction appeared only in some Leishmania-positive samples, never in viral ones. Uniquely, its antibody index fell steadily after treatment, making it a strong confirmatory test and a rare tool that can track recovery over time.
Catalog record
| CREATOR | Aroa Silgado, Alejandro Mediavilla, Patricia Martínez-Vallejo, Pau Bosch-Nicolau, Carles Rubio-Maturana, Lidia Goterris, Inés Oliveira-Souto, Núria Serre-Delcor, Joan Joseph-Munné, Israel Molina, Elena Sulleiro |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25643 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |