Characterization and pathogenicity of a novel triple-reassortant H6N6 avian influenza virus associated with reproductive failure in breeding ducks

Puduo Zhu, Liguo Gao, Zhihong Luo, Jiajia Liu, Xudong He, Qi Zhou, Qunhui Li, Zhuanqiang Yan, Wencheng Lin, Feng Chen · 2026

Read Characterization and pathogenicity of a novel triple-reassortant H6N6 avian influenza virus associated with reproductive failure in breeding ducks by Puduo Zhu, Liguo Gao, Zhihong Luo, Jiajia Liu, Xudong He, Qi Zhou, Qunhui Li, Zhuanqiang Yan, Wencheng Lin, Feng Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13343146.txt.

Description

Puduo Zhu and co-authors characterize a new H6N6 bird flu virus tied to breeding failure in ducks, in a 2026 study. Surveillance on affected duck farms isolated a strain whose genome mixes three distinct lineages, a triple reassortant, with two notable changes in its hemagglutinin protein.

Lab challenges showed the virus could infect mice, young Muscovy ducks, and clean laboratory chickens, causing mild illness in each. In breeding ducks, though, infection damaged the reproductive tract and sharply cut egg laying. Even low-harm bird flu, the authors warn, can cross species lines and hurt farm output, which makes steady flock surveillance essential for poultry regions.

Catalog record

CREATORPuduo Zhu, Liguo Gao, Zhihong Luo, Jiajia Liu, Xudong He, Qi Zhou, Qunhui Li, Zhuanqiang Yan, Wencheng Lin, Feng Chen
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36822
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13343146

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