Association of inflammation and serum adipocytokines with depression and anxiety burden in axial spondyloarthritis
Markéta Hušáková, Karel Pavelka, Karolína Kuchaříková, Jan Kotrs, Markéta Kuklová, Hana Hulejová, Ladislav Šenolt, Pavel Mohr, Marta Olejárová · 2026
Read Association of inflammation and serum adipocytokines with depression and anxiety burden in axial spondyloarthritis by Markéta Hušáková, Karel Pavelka, Karolína Kuchaříková, Jan Kotrs, Markéta Kuklová, Hana Hulejová, Ladislav Šenolt, Pavel Mohr, Marta Olejárová (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13342654.txt.
Description
Markéta Hušáková and eight co-authors linked fat-related hormones to mood in spine arthritis patients in a 2026 study. Axial spondyloarthritis inflames the spine and sacroiliac joints, and depression and anxiety ride along with it. The team measured four adipocytokines and the hunger hormone ghrelin in 93 patients and 100 matched healthy controls, alongside disease activity scores and standard mood questionnaires.
Patients scored clearly higher on depression and anxiety, with body-based symptoms strongest. Mood tracked disease activity tightly, but not body mass or spine damage. Two hormones stood out with opposite signs: doubling fetuin-A added roughly four depression points, while doubling resistin subtracted about two and a half. The authors read mood in this disease as driven mainly by inflammation, and urge early screening.
Catalog record
| CREATOR | Markéta Hušáková, Karel Pavelka, Karolína Kuchaříková, Jan Kotrs, Markéta Kuklová, Hana Hulejová, Ladislav Šenolt, Pavel Mohr, Marta Olejárová |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |