Visual acuities in patients with autosomal recessive retinitis pigmentosa associated with four rod phototransduction genes
Vishanna Balbirsingh, Shaima A. Hashem, Michalis Georgiou, Siying Lin, Gavin Arno, Mariya Moosajee, Andrew R. Webster, Michel Michaelides, Omar A. Mahroo · 2026
Read Visual acuities in patients with autosomal recessive retinitis pigmentosa associated with four rod phototransduction genes by Vishanna Balbirsingh, Shaima A. Hashem, Michalis Georgiou, Siying Lin, Gavin Arno, Mariya Moosajee, Andrew R. Webster, Michel Michaelides, Omar A. Mahroo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13342062.txt.
Description
Vishanna Balbirsingh and co-authors compare eyesight across gene faults in a 2026 eye study. Their patients have autosomal recessive retinitis pigmentosa, an inherited disease that slowly kills the retina, tied here to four genes that rods use to sense light.
Because those genes switch on at birth, patients often face night blindness early, long before wide rod loss begins. Side vision goes next as the outer retina fails, and sharp central sight can fall late in the disease. The team set visual acuity records side by side for the four genes, PDE6A, PDE6B, CNGA1, and CNGB1. Such gene-by-gene maps help doctors counsel families on what sight loss to expect.
Catalog record
| CREATOR | Vishanna Balbirsingh, Shaima A. Hashem, Michalis Georgiou, Siying Lin, Gavin Arno, Mariya Moosajee, Andrew R. Webster, Michel Michaelides, Omar A. Mahroo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 5 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |