Akkermansia muciniphila in cardiovascular diseases: opportunities and challenges
Shihao Li, Chuanmeng Zhang, Min Sha, He Zhu, Ming Chu · 2026
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Description
A celebrated gut microbe cuts both ways in heart disease, in a 2026 review by Shihao Li and colleagues on Akkermansia muciniphila. The mucus-living bacterium supports gut barrier repair, steadier glucose and lipids, and calmer immunity, protecting against hypertension, atherosclerosis, heart failure, and aortic aneurysm in studies.
Yet when the barrier is damaged or fiber is scarce, it can overgrow, chew through mucus, and worsen inflammation. Diet, drugs, and each person's starting microbiome shift its abundance, so blanket supplementation is risky. The authors call for strain-level clarity, safe dosing, and smarter delivery before clinical use.
Catalog record
| CREATOR | Shihao Li, Chuanmeng Zhang, Min Sha, He Zhu, Ming Chu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52659 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |