Associations of non-motor symptoms with perceptual speech impairments in Parkinson’s disease
Rui Liu, Ciara Leydon · 2026
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Description
Non-motor symptoms foreshadow speech decline in Parkinson's disease, in a 2026 study by Rui Liu and Ciara Leydon. Data came from 417 participants in the Parkinson's Progression Marker Initiative, followed over seven years with speech rated by both patients and examiners.
Baseline REM sleep behavior disorder raised the odds of worse speech at year seven (OR 1.58 for self-rated), as did autonomic dysfunction (OR 1.71). Examiner ratings showed a similar pattern. Since speech loss erodes well-being and self-awareness of decline varies widely, early non-motor clues could prompt timely speech therapy referrals before communication suffers badly.
Catalog record
| CREATOR | Rui Liu, Ciara Leydon |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36646 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |