Trends, survival and regional control of sentinel lymph node biopsy versus axillary dissection in cN0 breast cancer: a multicenter cohort in China
Jiang Wu, Jiahui Xiang, Dongxu Ma, Heng Cao, Zizhao Guo, Lin Cong, Ruijie Zhou, Xinke Shi, Yuchen Liu, Yansong Huang, Jiaqi Liu, Xiang Wang · 2026
Read Trends, survival and regional control of sentinel lymph node biopsy versus axillary dissection in cN0 breast cancer: a multicenter cohort in China by Jiang Wu, Jiahui Xiang, Dongxu Ma, Heng Cao, Zizhao Guo, Lin Cong, Ruijie Zhou, Xinke Shi, Yuchen Liu, Yansong Huang, Jiaqi Liu, Xiang Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13341454.txt.
Description
Less armpit surgery for early breast cancer is tracked across China by Jiang Wu and colleagues in a 2026 multicenter cohort study. The database held 53,758 women with node-negative-looking, stage T1-3 disease treated between 2013 and 2022, comparing sentinel node biopsy against full axillary dissection.
Sentinel biopsy use climbed from 18.8% to 75.3% in node-negative patients. In that group, five-year regional recurrence matched between approaches at about 1%. With positive nodes, recurrence ran higher after sentinel biopsy only in breast-conserving surgery (4.99% versus 1.27%), especially with fast-growing tumors, while mastectomy patients showed no clear difference. De-escalation looks safe for most, with caveats.
Catalog record
| CREATOR | Jiang Wu, Jiahui Xiang, Dongxu Ma, Heng Cao, Zizhao Guo, Lin Cong, Ruijie Zhou, Xinke Shi, Yuchen Liu, Yansong Huang, Jiaqi Liu, Xiang Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38612 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |