Exploratory analysis of neutrophil extracellular traps in synovial fluid and plasma from children with juvenile idiopathic arthritis
Lillemor Berntson, Caroline Sandström, Andreas Elfving, Fariborz Mobarrez · 2026
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Description
Tiny vesicles shed by neutrophils and platelets are hunted in children's arthritic joints by Lillemor Berntson's team in a 2026 pilot study. The exploratory work compared seven children with active, untreated juvenile idiopathic arthritis against ten healthy controls, sampling blood and joint fluid.
Flow cytometry found these vesicles in both blood and synovial fluid of every patient. Two plasma vesicle types ran significantly higher than in controls, and markers of neutrophil nets appeared in both compartments. Activated platelet vesicles stayed mostly in blood. No ties to disease activity scores emerged. The authors present this as a first map of these signals in the disease.
Catalog record
| CREATOR | Lillemor Berntson, Caroline Sandström, Andreas Elfving, Fariborz Mobarrez |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25841 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |