Hydrocortisone for prevention or treatment of bronchopulmonary dysplasia: long-term neurodevelopmental safety and efficacy—a meta-analysis of randomized clinical trials
Kawthar Ahmed Shehab, Rahaf Muslih N. Almatrafi, Ethar Ali, Yara Albargi, Sama Saabi, Halah Alhassan Aljohani, Rayan Nabil Almuhanna, Raghad Alnaami, Khalid Abdulrahman Almehery, Reema Safar Alamri, Sarah Ahmed A. Baqer, Shouq Naif Aloufi, Ahmed Elaraby, Bedah Mohammed Alnawfal · 2026
Read Hydrocortisone for prevention or treatment of bronchopulmonary dysplasia: long-term neurodevelopmental safety and efficacy—a meta-analysis of randomized clinical trials by Kawthar Ahmed Shehab, Rahaf Muslih N. Almatrafi, Ethar Ali, Yara Albargi, Sama Saabi, Halah Alhassan Aljohani, Rayan Nabil Almuhanna, Raghad Alnaami, Khalid Abdulrahman Almehery, Reema Safar Alamri, Sarah Ahmed A. Baqer, Shouq Naif Aloufi, Ahmed Elaraby, Bedah Mohammed Alnawfal (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13341419.txt.
Description
Hydrocortisone for premature infants' lung disease gets a long-term safety check in a 2026 meta-analysis led by Kawthar Ahmed Shehab. Because the older steroid dexamethasone raised fears of brain harm, the team pooled randomized trials of hydrocortisone against placebo or routine care, split by early or late dosing.
Seventeen reports from seven trials covered 2,213 infants. By age 2, death or developmental impairment struck 53.5% of the hydrocortisone group and 56.8% of controls, a gap that was not significant for either timing. Death rates also did not differ clearly. The pooled evidence neither proves benefit nor shows the feared harm.
Catalog record
| CREATOR | Kawthar Ahmed Shehab, Rahaf Muslih N. Almatrafi, Ethar Ali, Yara Albargi, Sama Saabi, Halah Alhassan Aljohani, Rayan Nabil Almuhanna, Raghad Alnaami, Khalid Abdulrahman Almehery, Reema Safar Alamri, Sarah Ahmed A. Baqer, Shouq Naif Aloufi, Ahmed Elaraby, Bedah Mohammed Alnawfal |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43812 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |