Human neural stem cell-derived extracellular vesicles improve cognitive function following glioma chemoradiation therapy

Casey Hudson, Robert P. Krattli, Sanad M. El-Khatib, Arya R. Vagadia, An H. Do, Shreya Madan, Manal T. Usmani, Tracy Nguyen, Devyani Swami, Katja M. Piltti, Leslie M. Thompson, Brian J. Cummings, Aileen J. Anderson, Munjal M. Acharya · 2026

Read Human neural stem cell-derived extracellular vesicles improve cognitive function following glioma chemoradiation therapy by Casey Hudson, Robert P. Krattli, Sanad M. El-Khatib, Arya R. Vagadia, An H. Do, Shreya Madan, Manal T. Usmani, Tracy Nguyen, Devyani Swami, Katja M. Piltti, Leslie M. Thompson, Brian J. Cummings, Aileen J. Anderson, Munjal M. Acharya (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13340850.txt.

Description

Casey Hudson and co-authors test stem cell vesicles to rescue thinking after brain tumor chemoradiation in a 2026 study. Radiation plus temozolomide extends glioma survival but often leaves lasting fog. Tiny vesicles shed by human neural stem cells carry cargo that calms inflammation and guards synapses.

Mice with and without brain tumors received the standard chemoradiation, then vesicles from two stem cell lines. Treated mice remembered better, and one vesicle type even stretched survival in tumor mice without therapy. Brain scans showed less scarring and healthier synapses, and tumor killing by the therapy stayed intact. A cell-free rescue is the hope.

Catalog record

CREATORCasey Hudson, Robert P. Krattli, Sanad M. El-Khatib, Arya R. Vagadia, An H. Do, Shreya Madan, Manal T. Usmani, Tracy Nguyen, Devyani Swami, Katja M. Piltti, Leslie M. Thompson, Brian J. Cummings, Aileen J. Anderson, Munjal M. Acharya
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE71 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13340850

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