Integrated gut microbiota and metabolome signatures revealed by deep metagenomic sequencing in post-stroke cognitive impairment with type 2 diabetes
Xiaoye Liu, Lai-Yu Kwok, Wenyi Zhang · 2026
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Description
Xiaoye Liu and colleagues probed gut microbes in 2026 in diabetic patients with thinking decline after stroke. Thinking decline after stroke gets worse with type 2 diabetes, yet gut microbe and body chemistry links were unclear. Stool samples from 28 diabetic patients with thinking decline and 29 matched controls went through deep gene sequencing and chemical profiling.
Overall diversity held steady, but germ and fungus mix shifted in small, telling ways. Butyrate making germs such as Lachnospira fell, while Butyricimonas virosa rose, and five fungus species including Torulaspora globosa declined. The gut brain signals point to new markers and possible aids for thinking decline after stroke in diabetes.
Catalog record
| CREATOR | Xiaoye Liu, Lai-Yu Kwok, Wenyi Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |