Adenovirus Infections in Hematologic Malignancy and Hematopoietic Cell Transplant Recipients: Epidemiology, Diagnosis, and Management
Scott Schoninger, Hyeon Mu Jang, Yeon Joo Lee · 2026
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Description
Scott Schoninger and colleagues review adenovirus infection in people with blood cancers and stem cell transplants, in a 2026 survey. Adenovirus can range from silent DNA in blood to pneumonia, gut disease, hepatitis, bladder bleeding, heart disease, and brain disease in these patients. Quantitative PCR now finds the virus earlier, but no agreed viral load cutoff guides treatment.
Risk climbs with T-cell depletion, cord blood transplant, severe graft-versus-host disease, high-dose steroids, and slow immune recovery, and children face higher rates than adults. Death remains substantial once virus spreads through blood or organs. The review weighs diagnosis, monitoring, and treatment options, helping transplant teams balance early action against drug toxicity.
Catalog record
| CREATOR | Scott Schoninger, Hyeon Mu Jang, Yeon Joo Lee |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |