Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues

Oscar O'Dwyer Lancaster‐Jones, Russell Quinn, Niloofar Khoshdel Rad, Kilian Paul, Andrea Frank, Daniela F Duarte Campos · 2026

Read Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues by Oscar O'Dwyer Lancaster‐Jones, Russell Quinn, Niloofar Khoshdel Rad, Kilian Paul, Andrea Frank, Daniela F Duarte Campos (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13336421.txt.

Description

Oscar O'Dwyer Lancaster-Jones and co-authors set quality benchmarks for blood vessel tissue assembled by sound in a 2026 tissue study. Acoustic handling can pattern cells without touching them, but nobody had defined how good the patterning must be for complex tissues to form.

The team made sound-patterned 3D vascular tissues and followed them for seven days. The tissues built their own vessel networks, secreted their own matrix, and shifted angiogenic gene activity in response to the acoustic patterning. Most tellingly, the quality of cell alignment tracked positively with the vascular structure that followed, so pattern quality predicts tissue growth. The method gives bioengineers measurable requirements, spanning biological and physical parameters, before acoustic assembly can be trusted for medical use.

Catalog record

CREATOROscar O'Dwyer Lancaster‐Jones, Russell Quinn, Niloofar Khoshdel Rad, Kilian Paul, Andrea Frank, Daniela F Duarte Campos
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE57829
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13336421

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