Mast cell burden and immunophenotype of Chinese patients with cutaneous mastocytosis: a 10-year study with focus on the easily neglected pathogenic features
Qiannan Jia, Xinran Li, Aiping Fan, Dian Zheng, Shuaixin Li, Weiqi Wang, Siying Li, Jun Li · 2026
Read Mast cell burden and immunophenotype of Chinese patients with cutaneous mastocytosis: a 10-year study with focus on the easily neglected pathogenic features by Qiannan Jia, Xinran Li, Aiping Fan, Dian Zheng, Shuaixin Li, Weiqi Wang, Siying Li, Jun Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13335676.txt.
Description
Qiannan Jia and co-authors characterized cutaneous mastocytosis in Chinese patients in a 2026 ten-year pathology study. The disease, driven by mast cell buildup in skin, varies widely in form, and its detailed features in Chinese patients were poorly mapped.
The cohort held 88 patients diagnosed by skin biopsy in a dermatology department between 2015 and 2024. Mast cell burden tracked with subtype: lowest in telangiectasia macularis eruptiva perstans, higher in urticaria pigmentosa, and highest in diffuse disease and mastocytoma. Heavy burden also went with raised lesions and earlier onset. Staining patterns for CD2, CD25, and CD30 differed by subtype and clustered with high-burden disease, offering diagnostic clues. The authors highlight easily neglected features that pathologists should watch for.
Catalog record
| CREATOR | Qiannan Jia, Xinran Li, Aiping Fan, Dian Zheng, Shuaixin Li, Weiqi Wang, Siying Li, Jun Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29018 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |