Efficacy and Safety of Navitor Versus Sapien Valves in Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis
Yusuf Ahmed, Abdulla Almubarak, Manar Ali, Jaafar Alsadeq Laith, Lujayn Juma, Walaa Yusuf, Zahraa Salman, Hana Asser, Mohamed Gabr, Ahmed Emara · 2026
Read Efficacy and Safety of Navitor Versus Sapien Valves in Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis by Yusuf Ahmed, Abdulla Almubarak, Manar Ali, Jaafar Alsadeq Laith, Lujayn Juma, Walaa Yusuf, Zahraa Salman, Hana Asser, Mohamed Gabr, Ahmed Emara (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13335009.txt.
Description
Yusuf Ahmed and colleagues compare 2026 Navitor and Sapien valves in transcatheter aortic valve implantation. Transcatheter aortic valve implantation is now a standard treatment for severe, symptom-causing aortic stenosis, above all in older patients. The meta-analysis compares the latest generations of self-expandable Navitor valves from Abbott Structural Heart with balloon-expandable Sapien valves from Edwards Lifesciences. The authors combed PubMed, Scopus, Web of Science, and the Cochrane Library for studies comparing the two valves.
The search turned up four studies covering 4,828 patients in total. The two groups did not differ in a statistical sense on device and technical success, 30-day all-cause death, stroke rate, or major vessel problems. Permanent pacemaker implantation was more common with Navitor valves, with a risk ratio of 2.16. The review gives heart teams a head-to-head safety and efficacy comparison for valve choice.
Catalog record
| CREATOR | Yusuf Ahmed, Abdulla Almubarak, Manar Ali, Jaafar Alsadeq Laith, Lujayn Juma, Walaa Yusuf, Zahraa Salman, Hana Asser, Mohamed Gabr, Ahmed Emara |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |