Rescue clazosentan for symptomatic cerebral vasospasm following subarachnoid hemorrhage due to anterior cranial fossa dural arteriovenous fistula: A case report with serial angiographic evaluation

Takahiro Morita, Yu Nomura, Takao Sasaki, Tomohiro Kaji, Kohsuke Katayama, Atsushi Saito · 2026

Read Rescue clazosentan for symptomatic cerebral vasospasm following subarachnoid hemorrhage due to anterior cranial fossa dural arteriovenous fistula: A case report with serial angiographic evaluation by Takahiro Morita, Yu Nomura, Takao Sasaki, Tomohiro Kaji, Kohsuke Katayama, Atsushi Saito (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13331172.txt.

Description

Takahiro Morita and colleagues report rescue use of clazosentan for brain vessel spasm after bleeding in a 2026 case. A 61-year-old man bled from a ruptured fistula in the front skull base. After surgical closure, preventive drug care failed to stop severe spasm in both front and middle brain arteries by day 10, with growing drowsiness.

Direct artery drug doses helped only briefly. Clazosentan then ran for 4 days as rescue care, and vessel imaging showed marked widening, most of all in small far vessels. Fluid build-up was handled with diuretics without breathing decline. No brain infarction arose, and the patient transferred out with a near-normal function score.

Catalog record

CREATORTakahiro Morita, Yu Nomura, Takao Sasaki, Tomohiro Kaji, Kohsuke Katayama, Atsushi Saito
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26722
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13331172

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