Predicting multiple long-term conditions with role limitation at age 46 using early-life data from the 1970 British Cohort Study

Kim Alipio, Sebastian Stannard, Nida Ziauddeen, Simon DS Fraser, Nisreen A Alwan · 2026

Read Predicting multiple long-term conditions with role limitation at age 46 using early-life data from the 1970 British Cohort Study by Kim Alipio, Sebastian Stannard, Nida Ziauddeen, Simon DS Fraser, Nisreen A Alwan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13331061.txt.

Description

Kim Alipio and colleagues test whether early-life data can predict multiple long-term conditions at midlife in a 2026 study. Data came from the 1970 British Cohort Study, covering 5,007 people at age 46. Records from birth and age 5 were tested as predictors of having two or more lasting conditions that limit daily roles.

In total, 11.9 percent of the group reported limiting multiple conditions in the reported outcome counts. Four models varied by data timing and outcome type. The best model, joining birth and age 5 data, still sorted risk only modestly, with an accuracy score of 0.66 in the given results. Kept predictors spanned shots, behaviour, asthma, and mother traits. Later childhood data may predict better.

Catalog record

CREATORKim Alipio, Sebastian Stannard, Nida Ziauddeen, Simon DS Fraser, Nisreen A Alwan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE51561
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13331061

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