Discovery of urinary metabolite biomarkers of psychiatric disorders using two-sample Mendelian randomization
Jihan K. Zaki, Jakub Tomasik, Jade A. McCune, Oren A. Scherman, Sabine Bahn · 2026
Read Discovery of urinary metabolite biomarkers of psychiatric disorders using two-sample Mendelian randomization by Jihan K. Zaki, Jakub Tomasik, Jade A. McCune, Oren A. Scherman, Sabine Bahn (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13330298.txt.
Description
Urine tests that hint at mental illness could speed up diagnosis, and a 2026 study by Zaki and co-authors hunts for such signs with gene data. Testing many people in labs is costly, so the team uses a gene-based method that mimics a natural trial. Data come from large public gene studies.
The scan covered seven mental disorders and many urine chemicals at once. It found dozens of links, and about a third were tied to just one disorder. Named links join an amino acid to schizophrenia and a muscle chemical to bipolar disorder, among others. The authors call the hits candidates, not proof, and urge lab follow-up. Cheap urine signs would be a welcome aid for clinics.
Catalog record
| CREATOR | Jihan K. Zaki, Jakub Tomasik, Jade A. McCune, Oren A. Scherman, Sabine Bahn |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |