Organoids in cancer therapy: translational applications and clinical promise
Mingzhen Bai, Maoyun Liu, Sheng Wang, Ming Ran, Jingyuan Ye, Yuqin Xie, Cheng Zhang, Yi Wang, Jiale Lu, Fengsheng Dai, Dewei Li, Hui Li · 2026
Read Organoids in cancer therapy: translational applications and clinical promise by Mingzhen Bai, Maoyun Liu, Sheng Wang, Ming Ran, Jingyuan Ye, Yuqin Xie, Cheng Zhang, Yi Wang, Jiale Lu, Fengsheng Dai, Dewei Li, Hui Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13330257.txt.
Description
Mini tumors grown in dishes from a patient own cancer cells keep that tumor layout and variety, making them a strong test bed for treatments. Mingzhen Bai and co-authors review how these organoids are moving toward real cancer care in this 2026 paper. Older flat cell cultures and mouse models miss much of what makes human tumors resist drugs.
Recent advances include organoids on microfluidic chips, printed organoids, and new-generation culture methods. The review covers drug screening, tailored therapy picks, and the hurdles of cost, speed, and standardization. Hospitals dream of testing a patient organoid panel before choosing chemotherapy. The authors judge that dream plausible but not yet routine, and they map what must improve for clinics to trust the results.
Catalog record
| CREATOR | Mingzhen Bai, Maoyun Liu, Sheng Wang, Ming Ran, Jingyuan Ye, Yuqin Xie, Cheng Zhang, Yi Wang, Jiale Lu, Fengsheng Dai, Dewei Li, Hui Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 69 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |