Circulating Methylated SEPT9 for Detection of Hepatocellular Carcinoma in Cirrhosis

Abderrahim Oussalah, Maël Silva Rodriguez, Guillaume Conroy, Mouni Bensenane, Hélène Rousseau, Ahmet Ayav, Jean-Louis Guéant, Houda Camara, Cédric Baumann, Valérie Laurent, Jean-Pierre Bronowicki · 2026

Read Circulating Methylated SEPT9 for Detection of Hepatocellular Carcinoma in Cirrhosis by Abderrahim Oussalah, Maël Silva Rodriguez, Guillaume Conroy, Mouni Bensenane, Hélène Rousseau, Ahmet Ayav, Jean-Louis Guéant, Houda Camara, Cédric Baumann, Valérie Laurent, Jean-Pierre Bronowicki (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13329740.txt.

Description

Abderrahim Oussalah and co-authors test a blood DNA marker to improve liver cancer detection in cirrhosis patients, in work from 2026. Liver cancer found early can be cured, but current watch methods miss many early cases. The standard blood marker alone lacks sensitivity.

The marker studied is a methyl-tagged gene fragment shed into blood. Patients at two French centers gave three blood samples each during routine watch visits. Marker calls were based on how many of the three samples tested positive. Cancer status was set by expert scan review blind to marker results. The study asks whether adding the marker to the standard test catches more cancers without excess false alarms.

Catalog record

CREATORAbderrahim Oussalah, Maël Silva Rodriguez, Guillaume Conroy, Mouni Bensenane, Hélène Rousseau, Ahmet Ayav, Jean-Louis Guéant, Houda Camara, Cédric Baumann, Valérie Laurent, Jean-Pierre Bronowicki
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13329740

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