Immune cell-derived membrane nanovesicles: A promethean fire for autoimmune disease therapy through immune cell mimicry

Yan Li, Nasrullah Jan, Jimin Zhang, Yang Qin, Gang Liu, Chao Liu · 2026

Read Immune cell-derived membrane nanovesicles: A promethean fire for autoimmune disease therapy through immune cell mimicry by Yan Li, Nasrullah Jan, Jimin Zhang, Yang Qin, Gang Liu, Chao Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13329390.txt.

Description

Yan Li and co-authors review tiny membrane bubbles drawn from immune cells as a possible therapy for autoimmune disease in a 2026 article. Current drugs often act broadly, cause side effects, and fail to restore immune tolerance. Bubbles shed by red blood cells, platelets, neutrophils, dendritic cells, or macrophages keep surface marks from their parent cells.

Those marks can guide bubbles to swollen tissue and calm immune action. Bubbles can also carry drug cargo or added targeting tags. The review covers making and loading methods, then uses in illnesses such as rheumatoid arthritis, lupus, bowel disease, and type 1 diabetes. Hurdles include large-scale making, keeping membranes intact, and loading cargo well. Fixes for those hurdles will decide clinical use.

Catalog record

CREATORYan Li, Nasrullah Jan, Jimin Zhang, Yang Qin, Gang Liu, Chao Liu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE130193
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13329390

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