From immunoinformatics insights to assay development: establishment of a peptide-based indirect elisa for cynomolgus tuberculosis detection
Dengling Huang, Mingjie Chen, Qiuyu Wu, Pengwei Liu, Leting Yang, Weixiang Huang, Kunhui Mo, Xiao Wei, Ying Tian, Jianhua Sun, Likun Gong · 2026
Read From immunoinformatics insights to assay development: establishment of a peptide-based indirect elisa for cynomolgus tuberculosis detection by Dengling Huang, Mingjie Chen, Qiuyu Wu, Pengwei Liu, Leting Yang, Weixiang Huang, Kunhui Mo, Xiao Wei, Ying Tian, Jianhua Sun, Likun Gong (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13328505.txt.
Description
Dengling Huang and colleagues report in 2026 on a new blood test for tuberculosis in captive cynomolgus monkeys. Older tests often miss cases or give false results, which makes screening whole colonies hard. The team used computer methods to search bacterial proteins for short pieces that trigger immune responses.
Their search found a peptide called MP71, taken from the MPT64 protein. They linked it to a carrier and built an indirect ELISA test around it. The test was checked in a learning group of 19 animals and a separate group of 21 animals. In the second group it found over 92 percent of cases with no false positives. The authors present it as a fast tool for routine colony checks.
Catalog record
| CREATOR | Dengling Huang, Mingjie Chen, Qiuyu Wu, Pengwei Liu, Leting Yang, Weixiang Huang, Kunhui Mo, Xiao Wei, Ying Tian, Jianhua Sun, Likun Gong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34935 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |