Rapid and quantitative phage susceptibility test by ramanome
Xiao Han, Xiaofu Wan, Yang Zhou, Xiaoting Fu, Xiaoshan Zheng, Bo Gao, Shi Huang, Anle Ge, Jiadong Huang, Hongzhou Lu, Jian Xu · 2026
Read Rapid and quantitative phage susceptibility test by ramanome by Xiao Han, Xiaofu Wan, Yang Zhou, Xiaoting Fu, Xiaoshan Zheng, Bo Gao, Shi Huang, Anle Ge, Jiadong Huang, Hongzhou Lu, Jian Xu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13327610.txt.
Description
Phage therapy needs a fast test for whether a virus can infect a patient's bacteria. Xiao Han and co-authors built one on Raman light fingerprints of bacterial chemistry. Their test reads how infection reshapes the cell's molecules, without waiting for visible lysis. Four Raman markers merge into one infection index. The test told susceptible from resistant bacteria within about an hour. It matched plaque assays in twenty-four of twenty-five checks.
The index also ranks how strongly a phage attacks a shared host. Tracking it over dose and time finds the lowest dose that keeps infection self-spreading. That floor defines a sane starting dose for therapy. The platform turns a yes-no test into a dosing tool.
Catalog record
| CREATOR | Xiao Han, Xiaofu Wan, Yang Zhou, Xiaoting Fu, Xiaoshan Zheng, Bo Gao, Shi Huang, Anle Ge, Jiadong Huang, Hongzhou Lu, Jian Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |