The changing epidemiology of human type 2 diabetes–associated atherosclerosis: Pathophysiological mechanisms and emerging treatment possibilities
Dania Al‐Sharify, Jiangming Sun, Andreas Edsfeldt · 2026
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Description
Dania Al-Sharify, Jiangming Sun, and Andreas Edsfeldt review how artery disease linked to type 2 diabetes is changing in a 2026 article. Heart and vessel events have fallen over the past decade, yet people with diabetes still carry about double the risk of those without it. The authors ask which plaque traits now set diabetic disease apart.
Recent human plaque studies find little difference in fat or inflammation markers, possibly because modern treatment already handles those routes well. Other traits stand out instead, such as thin fibrous caps and large dead cores, plus processes like oxidative stress and faulty clearing of dead cells. Targeting those less-treated routes may cut the remaining vessel risk in diabetes.
Catalog record
| CREATOR | Dania Al‐Sharify, Jiangming Sun, Andreas Edsfeldt |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57289 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |