Cardiac remodelling and clinical outcomes after mitral edge-to-edge repair with the PASCAL® system

Mareike Bladt, Marius Keller, Meinrad Gawaz, Juergen Schreieck, Andreas Goldschmied, Makoto Amaki, Takashi Matsumoto, Izumo Masaki, Shingo Kuwata, Shunsuke Kubo, Kentaro Hayashida, Firas Zahr, Felix Kreidel, Fabien Praz, Didier Tchétché, Harry Magunia, Monika Zdanyte, Tobias Geisler · 2026

Read Cardiac remodelling and clinical outcomes after mitral edge-to-edge repair with the PASCAL® system by Mareike Bladt, Marius Keller, Meinrad Gawaz, Juergen Schreieck, Andreas Goldschmied, Makoto Amaki, Takashi Matsumoto, Izumo Masaki, Shingo Kuwata, Shunsuke Kubo, Kentaro Hayashida, Firas Zahr, Felix Kreidel, Fabien Praz, Didier Tchétché, Harry Magunia, Monika Zdanyte, Tobias Geisler (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13326949.txt.

Description

Mareike Bladt and co-authors study heart changes and outcomes after clip repair of a leaky mitral valve in a 2026 paper. Long term leakage overloads the heart, swelling the upper chamber and stretching the lower one. The study asked how much the pressure relief from the clip turns into lasting reverse remodeling and clinical gain.

In 130 patients with severe symptoms, the clip raised cardiac index by about 11 percent and cut left atrial pressure by about 37 percent. Scans months later showed a smaller lower chamber width. Follow up tracked heart failure hospital stays and death at one year. Data sets were partial, with 86 patients for early flow measures and 73 for later scans.

Catalog record

CREATORMareike Bladt, Marius Keller, Meinrad Gawaz, Juergen Schreieck, Andreas Goldschmied, Makoto Amaki, Takashi Matsumoto, Izumo Masaki, Shingo Kuwata, Shunsuke Kubo, Kentaro Hayashida, Firas Zahr, Felix Kreidel, Fabien Praz, Didier Tchétché, Harry Magunia, Monika Zdanyte, Tobias Geisler
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13326949

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