Preventing Post-induction Hypotension During General Anaesthesia: A Dose-Response Study of Ringer’s Lactate Guided by the Inferior Vena Cava Collapsibility Index

Abhishek Chatterjee, Merina Sam, Himanshu Kumar, Deb Sanjay Nag, Bappaditya Pal, Aleena Wilson, Kakan Chakraborty · 2026

Read Preventing Post-induction Hypotension During General Anaesthesia: A Dose-Response Study of Ringer’s Lactate Guided by the Inferior Vena Cava Collapsibility Index by Abhishek Chatterjee, Merina Sam, Himanshu Kumar, Deb Sanjay Nag, Bappaditya Pal, Aleena Wilson, Kakan Chakraborty (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13326617.txt.

Description

Abhishek Chatterjee and team tested the best Ringer's lactate dose for stopping low blood pressure after being put to sleep. Their 2026 forward-looking, random treatment study took in 88 adults of ASA health status I or II, using ultrasound-guided lower vena cava collapsibility index to assess fluid responsiveness before general sleep. Low pressure after sleep is frequent and serious, linked to heart and kidney injury, yet preoperative volume assessment is often unreliable or invasive.

Patients given 10 ml per kilogram required mephentermine for a greater than 30% pressure fall, while no patient given 15 ml per kilo needed pressure-drug treatment. The higher dose better maintained upper, lower, and mean pressures. The authors recommend 15 ml per kilo of pre-sleep Ringer's lactate guided by vena cava scans, especially for high-pressure patients, as part of personal dynamic fluid management.

Catalog record

CREATORAbhishek Chatterjee, Merina Sam, Himanshu Kumar, Deb Sanjay Nag, Bappaditya Pal, Aleena Wilson, Kakan Chakraborty
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE19 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13326617

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