The impact of metabolic dysfunction-associated steatotic liver disease on non-invasive fibrosis scores in patients with chronic hepatitis B: a multicenter retrospective study
Yakup Gezer, Muhammet Rıdvan Tayşi, Arzu Tarakçı, Sevil Alkan, Selçuk Kaya, Zeynep Çelik, Sevgi Alan Doğan, Emre Bayhan, Selcen Özer Kökkızıl, Derya Tumer, Ahmet Doğan, Tuğba Demircioğlu, Oğuz Evlice, Ahmet Basutçu, Zeynep Burçin Yılmaz, Funda Memişoğlu, Ekrem Salduz, Esra Sağlam Kandemir, Mustafa Y · 2026
Read The impact of metabolic dysfunction-associated steatotic liver disease on non-invasive fibrosis scores in patients with chronic hepatitis B: a multicenter retrospective study by Yakup Gezer, Muhammet Rıdvan Tayşi, Arzu Tarakçı, Sevil Alkan, Selçuk Kaya, Zeynep Çelik, Sevgi Alan Doğan, Emre Bayhan, Selcen Özer Kökkızıl, Derya Tumer, Ahmet Doğan, Tuğba Demircioğlu, Oğuz Evlice, Ahmet Basutçu, Zeynep Burçin Yılmaz, Funda Memişoğlu, Ekrem Salduz, Esra Sağlam Kandemir, Mustafa Y (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13326284.txt.
Description
Yakup Gezer and team tested how fatty liver disease affects noninvasive scarring scores in chronic hepatitis B. Their 2026 multi-site look-back study studied patients with the virus who had liver biopsy, calling major scarring ISHAK stage 3 or higher and fatty buildup as at least 5% fat on biopsy. Twenty simple tests were set side by side, including newer scores FIB-8 and FIB-9 made for fatty liver disease but new in combined virus and fatty liver disease.
Test results varied by fatty liver status: FIB-8, Lok, and ATA scores performed significantly better in patients with fatty liver disease, suggesting metabolic factors shape how well scarring markers discriminate. Across all groups, however, every test showed only low-to-moderate results, limiting standalone clinical use. The authors conclude that fatty liver status must be considered when interpreting scarring scores in the virus, and that more accurate simple models are still needed here.
Catalog record
| CREATOR | Yakup Gezer, Muhammet Rıdvan Tayşi, Arzu Tarakçı, Sevil Alkan, Selçuk Kaya, Zeynep Çelik, Sevgi Alan Doğan, Emre Bayhan, Selcen Özer Kökkızıl, Derya Tumer, Ahmet Doğan, Tuğba Demircioğlu, Oğuz Evlice, Ahmet Basutçu, Zeynep Burçin Yılmaz, Funda Memişoğlu, Ekrem Salduz, Esra Sağlam Kandemir, Mustafa Y |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |