A 3D Bioprinted Platform That Maintains the Functional Integrity of Primary AML Cells
Wanling Huang, Bo Deng, Nini Guo, Yiyi Ding, Zhangjingwen Xu, Yiwen Lu, Yue Ma, Qian Ren, Nan Wang, Pengyu Huang, Xiaotong Ma · 2026
Read A 3D Bioprinted Platform That Maintains the Functional Integrity of Primary AML Cells by Wanling Huang, Bo Deng, Nini Guo, Yiyi Ding, Zhangjingwen Xu, Yiwen Lu, Yue Ma, Qian Ren, Nan Wang, Pengyu Huang, Xiaotong Ma (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13325942.txt.
Description
Wanling Huang and colleagues build a 3D bioprinted home for primary leukemia cells in a 2026 study. Acute myeloid leukemia cells fade fast in flat dishes, which makes drug testing unreliable.
Patient bone marrow cells were printed inside a gelatin and hyaluronic acid gel tuned to feel like real marrow. Inside the gel, the cells lived longer, kept dividing, and held onto stem-like groups. Their drug responses also matched clinical behavior more closely than dish cultures. Gene profiles showed MYC and mTORC1 programs switched on, with both energy routes running hot. The patient-specific setup could sharpen preclinical drug screening.
Catalog record
| CREATOR | Wanling Huang, Bo Deng, Nini Guo, Yiyi Ding, Zhangjingwen Xu, Yiwen Lu, Yue Ma, Qian Ren, Nan Wang, Pengyu Huang, Xiaotong Ma |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54201 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |