Seizure Mimics as the Presenting Feature of a Functional Metastatic Pancreatic Neuroendocrine Tumour in a Patient With Pre-existing Epilepsy: A Diagnostic Challenge
Itizaz Hayat, Taimoor Tahir, Maheen Omer, Ibrahim Elzeiny, May Loo · 2026
Read Seizure Mimics as the Presenting Feature of a Functional Metastatic Pancreatic Neuroendocrine Tumour in a Patient With Pre-existing Epilepsy: A Diagnostic Challenge by Itizaz Hayat, Taimoor Tahir, Maheen Omer, Ibrahim Elzeiny, May Loo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13325716.txt.
Description
Itizaz Hayat and team report a pancreatic tumor that posed as epilepsy in a man who had it. Their 2026 case paper follows a 74-year-old man, seizure-free for 11 years on carbamazepine, with advanced grade 3 pancreatic neuroendocrine tumor. He was taken in after two to three weeks of night muddling, sweats, bad dreams, fret, and odd movements. The episode was first blamed on seizure return or muddling, and brain imaging, drug levels, and immune testing were normal.
Fasting tests found the cause: after three hours without food, insulin and proinsulin were markedly high with a negative drug screen, fulfilling criteria for endogenous excess insulin. A scan found liver metastases and uptake in the pancreatic tail, confirming an insulin-secreting primary. Diazoxide and monthly lanreotide could not halt decline, and the man died on palliative care. The authors urge glucose measure during any witnessed episode, a step that saves lives.
Catalog record
| CREATOR | Itizaz Hayat, Taimoor Tahir, Maheen Omer, Ibrahim Elzeiny, May Loo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |