Mixing Regime Controlled Kinetics of Amorphous Calcium Phosphate Formation and Transformation

Özgür Gülmez, Eren Demirbilek, Seniz Ucar · 2026

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Description

Özgür Gülmez, Eren Demirbilek, and Seniz Ucar watch how mixing style steers early calcium phosphate crystals in a 2026 study. The amorphous form often appears first in bone-like mineral growth, then converts to hydroxyapatite.

Live pH and calcium sensors tracked precipitation while the order of pouring calcium and phosphate solutions was swapped. Every run followed a two-step path through the amorphous stage. Pouring phosphate into calcium delayed crystal birth and stretched the amorphous lifetime. Additives stretched it further, with citrate beating the protein BSA. The delays traced back to pH paths and brief oversaturation set during mixing. The cheap sensor setup offers labs a live window on mineral birth.

Catalog record

CREATORÖzgür Gülmez, Eren Demirbilek, Seniz Ucar
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37574
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13325383

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