Surface-Density-Controlled Spreading–Packing Competition in Antibody Monolayers Revealed by PM-IRRAS and 2D Correlation Spectroscopy
Matteo Piscitelli, Cinzia Di Franco, Lucia Sarcina, Michele Catacchio, Fabrizio Corvino, Eleonora Macchia, Luisa Torsi, Gaetano Scamarcio · 2026
Read Surface-Density-Controlled Spreading–Packing Competition in Antibody Monolayers Revealed by PM-IRRAS and 2D Correlation Spectroscopy by Matteo Piscitelli, Cinzia Di Franco, Lucia Sarcina, Michele Catacchio, Fabrizio Corvino, Eleonora Macchia, Luisa Torsi, Gaetano Scamarcio (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13325138.txt.
Description
Matteo Piscitelli and colleagues chart how antibody layers reshape themselves on gold in a 2026 surface study. Antibodies stuck to sensors and chips form the working face of many tests, yet their layout is hard to predict.
Anti-IgM antibodies were laid from solutions spanning 0.5 to 1000 micrograms per mL for times from 1 to 330 minutes. Infrared spectra read the protein structure at each stage. At low coverage the antibodies sprawled in loose, partly disordered shapes. Crowding and time pushed them into compact, beta-sheet-rich packs. A single surface-density score merged dose and time into one axis that maps the contest between spreading and packing.
Catalog record
| CREATOR | Matteo Piscitelli, Cinzia Di Franco, Lucia Sarcina, Michele Catacchio, Fabrizio Corvino, Eleonora Macchia, Luisa Torsi, Gaetano Scamarcio |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38229 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |