Exercise-induced hypoalgesia in healthy males is best explained by mechanisms selectively affecting deep-tissue pain sensitivity within exercising body parts
Vladimir Aron, Thomas Graven-Nielsen, Louise Deldicque, André Mouraux · 2026
Read Exercise-induced hypoalgesia in healthy males is best explained by mechanisms selectively affecting deep-tissue pain sensitivity within exercising body parts by Vladimir Aron, Thomas Graven-Nielsen, Louise Deldicque, André Mouraux (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13324681.txt.
Description
Vladimir Aron and colleagues locate where exercise dulls pain in a 2026 experiment with healthy young men. One hard workout briefly lowers pain sensitivity, but whether the effect is body-wide or local was unclear.
Thirty-eight men aged 18 to 30 cycled for 25 minutes at strong effort or at light effort as a control. Before and after, the team tested pressure, heat, cold, and pinprick sensitivity in the worked legs and the resting arms. Hard cycling raised pressure pain thresholds only in the legs. Other measures barely moved, and hearing checks stayed flat. The pattern points to deep tissue sensors inside the working muscles as the main site of the effect.
Catalog record
| CREATOR | Vladimir Aron, Thomas Graven-Nielsen, Louise Deldicque, André Mouraux |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 77514 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |