Enhancing diabetes treatment by targeted nucleic acid and drug delivery using cell-penetrating peptides, peptide nucleic acids, and receptor targeting

Bozidarka L. Zaric, Sara Khodahemmati, Sonja S. Zafirovic, Esma R. Isenovic · 2026

Read Enhancing diabetes treatment by targeted nucleic acid and drug delivery using cell-penetrating peptides, peptide nucleic acids, and receptor targeting by Bozidarka L. Zaric, Sara Khodahemmati, Sonja S. Zafirovic, Esma R. Isenovic (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13324655.txt.

Description

Bozidarka L. Zaric and colleagues review precision delivery tools for type 2 diabetes drugs and genes in a 2026 article. Hitting the right tissue hard while sparing the rest could raise benefit and cut side effects.

Three delivery families anchor the review. Cell-penetrating peptides ferry cargo across cell membranes, while peptide nucleic acids bind gene targets tightly and resist breakdown by enzymes. Antibodies and receptor ligands steer loads toward pancreas beta cells and other metabolic tissues. The authors set out the strengths of each route, from the neutral charge of peptide nucleic acids to fragment-based antibody designs. Together the methods point toward gene control tuned to insulin signaling and beta cell health.

Catalog record

CREATORBozidarka L. Zaric, Sara Khodahemmati, Sonja S. Zafirovic, Esma R. Isenovic
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE81862
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13324655

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