The association between maternal multivitamin intake and premature birth
Jia Sun, Yiming Zhang, Zhengmin Qian, Pamela K. Xaverius, Hong Xian, Morgan LeBaige · 2026
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Description
Jia Sun and team checked whether self-chosen vitamin use around pregnancy relates to premature birth. Their 2026 secondary analysis drew on a nested case-control study within a large prospective cohort in Wuhan, China, covering 6,656 births from 2011 to 2013. Intake was checked both before conception and while pregnant, with models that allowed for social, lifestyle, and medical factors.
Vitamin use in both periods was linked with higher odds of doctor-ordered early birth, with an adjusted odds ratio of 1.54. The authors stress that causality cannot be confirmed: exposure assessment was limited, residual confounding remains, and reverse causation is possible, since complications may prompt supplement use. While vitamins matter for maternal health, they cannot replace medical prevention of early birth, and the authors call for monitoring vitamin levels and clearer provider guidance.
Catalog record
| CREATOR | Jia Sun, Yiming Zhang, Zhengmin Qian, Pamela K. Xaverius, Hong Xian, Morgan LeBaige |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |