Multicentre comparative study of neural epidermal growth factor-like 1 protein vs M-type phospholipase A2 receptor-associated membranous nephropathy
Subrahmanian Sathiavageesan, Abirami Krishnan, Krishnaswamy Sampathkumar, Ranjanee Muthu · 2026
Read Multicentre comparative study of neural epidermal growth factor-like 1 protein vs M-type phospholipase A2 receptor-associated membranous nephropathy by Subrahmanian Sathiavageesan, Abirami Krishnan, Krishnaswamy Sampathkumar, Ranjanee Muthu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13324629.txt.
Description
Subrahmanian Sathiavageesan and team compared two antigenic variants of membranous nephropathy head to head for the first time. Their 2026 retrospective cohort contrasted 17 patients with NELL1-linked disease against 24 with PLA2R-linked disease diagnosed in the same period, using time-to-event analysis with remission, complete or partial, as the primary outcome. PLA2R disease is the most common variant, followed by NELL1, yet direct outcome comparisons had been few.
NELL1 disease carried a favorable prognosis: higher remission rates, faster time to remission, more spontaneous remission, and less treatment-resistant nephrotic syndrome. Prior exposure to usual indigenous medicines was more common in the NELL1 group, a link the authors note for further study. They argue that antigen-specific outcome research can sharpen prognosis and guide treatment choices in membranous nephropathy, rather than treating all variants alike.
Catalog record
| CREATOR | Subrahmanian Sathiavageesan, Abirami Krishnan, Krishnaswamy Sampathkumar, Ranjanee Muthu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |