Post-transplant metabolic dysregulation: Insights and implications for kidney graft survival
Tabassum Elahi, Saima Ahmed, Muhammed Mubarak · 2026
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Description
Tabassum Elahi, Saima Ahmed, and Muhammed Mubarak review the metabolic fallout of kidney transplant and its threat to graft life. Their 2026 paper notes that transplant improves how long people live and quality of life in end-stage kidney disease, yet such disorders are common afterward and endanger both graft and patient. Post-transplant diabetes strikes up to 30% of patients within a year, while transient high blood sugar affects 60% of nondiabetic patients after surgery.
Dyslipidemia, obesity, high uric acid, and secondary hyperparathyroidism add cardiovascular, bone, and graft risks, and immune drugs including corticosteroids, calcineurin drugs, and mTOR drugs contribute a lot. The review weighs lifestyle change, drugs such as SGLT2 drugs and GLP-1 receptor agonists, bariatric options, and close weight monitoring as countermeasures. Evidence gaps remain, above all in managing hyperparathyroidism, and the authors call for tighter tracking after transplant.
Catalog record
| CREATOR | Tabassum Elahi, Saima Ahmed, Muhammed Mubarak |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |