Plant-derived extracellular vesicles as bioactive nanoplatforms: Biogenesis, therapeutic evidence, and translational challenges
Jingcheng Yu, Yuren Shen, Hao Jia · 2026
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Description
Jingcheng Yu, Yuren Shen and Hao Jia review plant-derived vesicles as therapy platforms, in a 2026 mini-review. Their angle is drug development, not pure biology. These nanoscale sacs come from edible and medicinal plants. They mix natural bioactivity with the scale gains of a natural carrier.
Formation, isolation and testing are compared with mammalian exosomes and synthetic liposomes. Early studies cover bone repair, nerve injury, gut inflammation, cancer and kidney stone disease. The authors weigh dose spread, model limits and mechanism strength in each area. Vesicles also serve as carriers for added drugs. Messy naming and uneven purification are key barriers. Thin drug-tracking data and scarce clinical proof also hold the field back.
Catalog record
| CREATOR | Jingcheng Yu, Yuren Shen, Hao Jia |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29643 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |