Fatty acid β-oxidation-associated prognostic model in gastric cancer and functional validation of IL-6 as a potential therapeutic target
Chao Qu, Xuetao Yuan, Shuting Yang, Yifan Qiao, Renjianzhi Zhang, Yunhua Wu, Mengke Zhu, Jiayin Du, Gan Li, Rui Zhang, Xuejun Sun, Xuqi Li · 2026
Read Fatty acid β-oxidation-associated prognostic model in gastric cancer and functional validation of IL-6 as a potential therapeutic target by Chao Qu, Xuetao Yuan, Shuting Yang, Yifan Qiao, Renjianzhi Zhang, Yunhua Wu, Mengke Zhu, Jiayin Du, Gan Li, Rui Zhang, Xuejun Sun, Xuqi Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13324250.txt.
Description
Chao Qu and co-authors build a risk model for stomach cancer from genes tied to fat burning, in a 2026 paper. Fatty acid oxidation, the cell's way of burning fat for fuel, may shape how this cancer grows. The team mined public gene data sets and found 160 genes tied to the process.
Ten of those genes formed a signature that split patients into high and low risk groups. The team checked gene changes, immune cell entry, and drug response in each group, and built a chart to guess patient outlook. One signal protein, IL-6, stood out in lab checks of cells and tissue. The authors offer it as a marker and drug target.
Catalog record
| CREATOR | Chao Qu, Xuetao Yuan, Shuting Yang, Yifan Qiao, Renjianzhi Zhang, Yunhua Wu, Mengke Zhu, Jiayin Du, Gan Li, Rui Zhang, Xuejun Sun, Xuqi Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |