A specific basal forebrain–medial prefrontal cholinergic pathway improves attentional control in male mice
Giulia R Fois, Maria-Carmen Medrano, Rémi Proville, Stephanie Caille, Karine Guillem · 2026
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Description
Giulia Fois and a team of co-authors trace a brain path that sharpens attention in mice, in a paper dated twenty twenty-six. A chemical messenger, acetylcholine, feeds the front brain region that balances focus and restraint. The team recorded and steered the circuit during a cued number task.
One sub-region quieted after a brief start burst, and that quiet seemed needed to finish response chains well. Its chemical supply came almost solely from one basal forebrain zone. Switching that supply on calmed the region and raised optimal responses. The map refines how attention circuits are wired.
Catalog record
| CREATOR | Giulia R Fois, Maria-Carmen Medrano, Rémi Proville, Stephanie Caille, Karine Guillem |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |