Editorial: Updates and discussions about basal ganglia and their circuits
José Rodolfo Lopes de Paiva Cavalcanti, Expedito Silva do Nascimento-Júnior, Zhi-Li Huang, Adhil Bhagwandin · 2026
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Description
José Rodolfo Lopes de Paiva Cavalcanti and co-editors introduce a collection on the basal ganglia and their circuits, in a 2026 editorial. These deep brain nuclei, spanning striatum, pallidum, subthalamic nucleus and substantia nigra, were long cast as movement controllers alone.
Current views add cognition, motivation, reward and emotion to their remit, carried by dopamine, glutamate and GABA links. Classic direct, indirect and hyperdirect pathway models still frame debate, with the direct path easing movement and the indirect path holding it back. Featured work updates those models against disorders such as Parkinson's and Huntington's disease. The editors frame the set as a step toward circuit-level treatment ideas.
Catalog record
| CREATOR | José Rodolfo Lopes de Paiva Cavalcanti, Expedito Silva do Nascimento-Júnior, Zhi-Li Huang, Adhil Bhagwandin |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 5299 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |