Extracorporeal Membrane Oxygenation in the Interstage Period After Norwood and Related Stage I Palliations in Infants With Single Ventricle: A Systematic Review of Incidence, Risk Factors, and Outcomes

Dongzhe Li, Stephen J Bottrell, Stephen B Horton, Christian P Brizard, Salvatore Pepe · 2026

Read Extracorporeal Membrane Oxygenation in the Interstage Period After Norwood and Related Stage I Palliations in Infants With Single Ventricle: A Systematic Review of Incidence, Risk Factors, and Outcomes by Dongzhe Li, Stephen J Bottrell, Stephen B Horton, Christian P Brizard, Salvatore Pepe (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13323580.txt.

Description

Dongzhe Li and co-authors review ECMO use between heart surgery stages in babies born with a single ventricle, in a 2026 systematic review. The first-stage Norwood operation carries high risk of heart failure, often needing this life-support circuit before the next stage.

Searching four databases for work from 1990 to March 2026, they kept 15 studies with 4,030 patients. Pooled ECMO use after Norwood surgery reached 18.1 percent of cases in their estimate, and hospital survival for supported babies ranged widely with no clear gain over time. Low birth weight, long bypass, valve leakage and complex anatomy raised ECMO risk. Longer runs and complications such as brain injury, kidney failure and bleeding worsened outcomes.

Catalog record

CREATORDongzhe Li, Stephen J Bottrell, Stephen B Horton, Christian P Brizard, Salvatore Pepe
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE54497
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13323580

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