Impact of preoperative skeletal muscle mass on the healing time of postoperative pancreatic fistula after pancreaticoduodenectomy

Takuro Takeuchi, Yoshito Tomimaru, Hirofumi Akita, Yosuke Mukai, Kazuki Sasaki, Shinichiro Hasegawa, Daisaku Yamada, Takehiro Noda, Yuichiro Doki, Hidetoshi Eguchi · 2026

Read Impact of preoperative skeletal muscle mass on the healing time of postoperative pancreatic fistula after pancreaticoduodenectomy by Takuro Takeuchi, Yoshito Tomimaru, Hirofumi Akita, Yosuke Mukai, Kazuki Sasaki, Shinichiro Hasegawa, Daisaku Yamada, Takehiro Noda, Yuichiro Doki, Hidetoshi Eguchi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13323506.txt.

Description

Takuro Takeuchi and nine co-authors ask whether a patient's muscle mass before pancreas surgery affects how fast a leak heals. A pancreatic fistula, where digestive juice leaks after the Whipple operation, is a feared complication. Most past work studied who gets one, not how long healing takes.

Their 2026 study covers patients whose leaks reached grade B or C. Healing time ran from surgery until all treatment drains came out, averaging about 40 days. Patients with low muscle mass on pre-surgery scans healed much more slowly, about 46 days against 37 for the well-muscled group. The gap survived statistical checks. Muscle, now seen as a signaling organ, may actively support repair, not just strength.

Catalog record

CREATORTakuro Takeuchi, Yoshito Tomimaru, Hirofumi Akita, Yosuke Mukai, Kazuki Sasaki, Shinichiro Hasegawa, Daisaku Yamada, Takehiro Noda, Yuichiro Doki, Hidetoshi Eguchi
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13323506

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