The CRISPR-Cas toolkit for mosquito-borne virus surveillance: detection, tracing, and discovery
Yang Wu, Huiling Cai, Qipeng Wu, Jie Wu, Jia Hu, Enjiong Huang, Zhongqi Li, Shaojun Liang, Xuefeng Hu, Jun Dai, Ruyan Liao · 2026
Read The CRISPR-Cas toolkit for mosquito-borne virus surveillance: detection, tracing, and discovery by Yang Wu, Huiling Cai, Qipeng Wu, Jie Wu, Jia Hu, Enjiong Huang, Zhongqi Li, Shaojun Liang, Xuefeng Hu, Jun Dai, Ruyan Liao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13323464.txt.
Description
Yang Wu leads a review of CRISPR tools for tracking mosquito-borne viruses, published in 2026, across detection, tracing and discovery support. Surveillance must catch many co-circulating pathogens, types and lineages quickly at clinics and mosquito sampling sites.
Detection is the most mature use, with Cas12 and Cas13 assays for Zika, dengue, West Nile virus, chikungunya, Japanese encephalitis and kin reporting sub-hour runs and portable readouts. Tracing still leans on portable sequencing, while CRISPR sample preparation tricks remain transferable ideas rather than field standards. Multiplex systems such as CARMEN can screen known viruses, but finding truly new ones still needs metagenomic sequencing. Field proof in pooled mosquito samples stays thin.
Catalog record
| CREATOR | Yang Wu, Huiling Cai, Qipeng Wu, Jie Wu, Jia Hu, Enjiong Huang, Zhongqi Li, Shaojun Liang, Xuefeng Hu, Jun Dai, Ruyan Liao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 68133 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |