Impact of high disease activity on damage accrual and disease outcomes in childhood-onset systemic lupus erythematosus
Ninlapat Jidmahawong, Butsabong Lerkvaleekul, Kwanchai Pirojsakul, Soamarat Vilaiyuk · 2026
Read Impact of high disease activity on damage accrual and disease outcomes in childhood-onset systemic lupus erythematosus by Ninlapat Jidmahawong, Butsabong Lerkvaleekul, Kwanchai Pirojsakul, Soamarat Vilaiyuk (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13323140.txt.
Description
Ninlapat Jidmahawong and colleagues measure how high disease activity harms children with lupus, in a 2026 retrospective cohort study. Their set held 196 patients with childhood-onset systemic lupus erythematosus, diagnosed at a mean age near 11 years and each followed for a year or more.
About two thirds spent some time in high activity, defined by a SLEDAI-2K score of 10 or more in their rules. Those patients accrued organ damage far more often than the rest, and the share of time spent in high activity tracked damage in a dose-like way. Higher time thresholds carried sharply higher hazards of damage. The authors argue for tight, sustained control of activity in childhood lupus.
Catalog record
| CREATOR | Ninlapat Jidmahawong, Butsabong Lerkvaleekul, Kwanchai Pirojsakul, Soamarat Vilaiyuk |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43378 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |