Cross-talk among novel programmed cell death pathways: a decisive network in renal ischemia-reperfusion injury

Yalin Lou, Jueheng Wu, Shilei Cheng, Guanghan Wu, Liang Guo, Fan Yang, Jianbo Wu · 2026

Read Cross-talk among novel programmed cell death pathways: a decisive network in renal ischemia-reperfusion injury by Yalin Lou, Jueheng Wu, Shilei Cheng, Guanghan Wu, Liang Guo, Fan Yang, Jianbo Wu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13322891.txt.

Description

Yalin Lou and co-authors describe linked cell death paths in kidney injury after blood flow returns, in a 2026 review. The injury is a main cause of acute kidney failure, and no strong treatment exists yet. Newer death forms covered include pyroptosis, ferroptosis, cuproptosis and necroptosis.

These paths do not act alone. They cross-talk in set cell types and at set phases of injury. Together they drive a cycle of inflammation and cell stress that harms kidney tubules. Treating one path alone may thus fail. The authors assess current drugs against this network view. They propose combined treatments, patient grouping by death-path markers, and smart nano-scale systems that can adjust key points over time.

Catalog record

CREATORYalin Lou, Jueheng Wu, Shilei Cheng, Guanghan Wu, Liang Guo, Fan Yang, Jianbo Wu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE78128
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13322891

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